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Industrial News

  • A summary of 45 gene therapy drugs that have been marketed around the world

    Genes are the basic genetic units that control traits. Except for the genes of some viruses, which are composed of RNA, the genes of most organisms are composed of DNA . Most diseases of organisms are caused by the interaction between genes and the environment. Gene therapy can essentially cure o...
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  • In the era of RNA therapy, who can become the “new darling” of the industry  | Annual inventory

    In the era of RNA therapy, who can become the “new darling” of the industry | Annual inventory

    Source: WuXi AppTec   Recent years, the field of RNA therapy has shown an explosive trend- in the past 5 years alone, 11 RNA therapies have been approved by the FDA, and this number even exceeds the sum of previously approved RNA therapies! Compared with traditional therapies, RNA therapy ca...
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  • Ordinary PCR, fluorescent PCR, digital PCR; analysis of advantages and disadvantages!

    Ordinary PCR, fluorescent PCR, digital PCR; analysis of advantages and disadvantages!

    Several revolutionary inventions in the history of detection technology in my mind are immunolabeling technology based on the principle of antigen-antibody specific binding, PCR technology and sequencing technology. Today we will talk about PCR technology. According to t...
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  • Summary|As of August 2022, 41 gene therapy drugs have been launched worldwide.

    Summary|As of August 2022, 41 gene therapy drugs have been launched worldwide.

    Recently, three gene therapy drugs have been approved for marketing, namely: (1) On July 21, 2022, PTC Therapeutics, Inc. (NASDAQ: PTCT) announced that its AAV gene therapy Upstaza™ was approved by the European Commission It is the first marketed gene therapy directly in...
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  • The Past and Present Of CACLP

    The Past and Present Of CACLP

    From October 26th to 28th, 2022, a new feast of experimental medicine and in vitro diagnosis – The 19th China China Association of Clinical Laboratory Practice Expo The 2nd China IVD Supply Chain Expo (CISCE) was successfully held at Nanchang Greenland International Expo Center. FOREGENE Co...
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  • PCR machine|Do you really understand?

    PCR machine|Do you really understand?

    PCR machine|Do you really understand? Nobel Prize-winning PCR technology In 1993, American scientist Mulis received the Nobel Prize in Chemistry, and his achievement was the invention of PCR technology. The magic of PCR technology is in the following characteristics: Firstly, the amount of DNA to...
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  • Latest Nature Thesis: Analyze the structure and cutting DNA mechanism of the new gene editing tool ISRB

    Latest Nature Thesis: Analyze the structure and cutting DNA mechanism of the new gene editing tool ISRB

    In the past ten years, the gene editing technology based on CRISPR has developed rapidly, and has been successfully applied to the treatment of genetic diseases and cancer in human clinical trials. At the same time, scientists around the world are constantly tap new new tools with gene editing po...
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  • Gene therapy, completely “wake up” the ear

    Gene therapy, completely “wake up” the ear

    Hearing loss (HL) is the most common sensory disability disease in humans. In developed countries, about 80% of prelingual deafness cases in children are caused by genetic factors. The most common are single-gene defects (as shown in Fig. 1), 124 gene mutations have been found to be associated wi...
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  • An overview of the article–RNase inhibitors

    An overview of the article–RNase inhibitors

    Authors: Wang Xiaoyan, Zhao Eryu Unit: Jiaozhou Hospital, Dongfang Hospital Affiliated to Tongji University At present, the main sample type for respiratory pathogen nucleic acid detection is throat swab. There are many kinds of commonly used sample preservation solutions, all of which need to be...
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  • Understand RT-qPCR in one article

    Understand RT-qPCR in one article

    Starting material: RNA Quantitative reverse transcription PCR (RT-qPCR) is an experimental method used in PCR experiments using RNA as the starting material. In this method, total RNA or messenger RNA (mRNA) is first transcribed into complementary DNA (cDNA) by reverse transcriptase. Subsequently...
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  • Fluorescence quantitative PCR

    W:Brother, the reverse transcription is completed, and finally the last step – fluorescent quantitative PCR! Hey, brother, what is real-time quantitative PCR? M:PCR you always know, right? W:You know, PCR is the polymerase chain reaction, and it is a technology that increases DNA! M:It̵...
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  • RNA extraction preparation and precautions

    Sterilization of pipette tips and EP tubes, etc. 1. Prepare 0.1% (one thousandth) DEPC (highly toxic substance) with deionized water, use it carefully in a fume hood, and store it at 4°C away from light; DEPC water is pure water treated with DEPC and sterilized by high temperature and high pressu...
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